
Design, Fabrication Strategy and Demonstrations of Neuroworm. Credit: Nature (2025). Doi: 10.1038/s41586-025-0934- W
In Brain-Computer Interfaces (BCIS) and other Neural Implant Systems, Electrodes Serve as the Critical Interface and Are Core Sensors Linking Electronic Devices with Bioological NROLOGION NERVOUS SYVOUS SYVOUN Most Currently Implanted Electrodes are Static: Once positioned, they remain fixed, Sampling Neural Activity from Onaly a Limited Region. Over time, they often Elicit Immune Responses, Suffer Signal Degradation, Or Fail Entrely, which has hindred the broader application and transformative potential of bcis.
In a study Published in NatureA Team LED by Prof. Liu zhiyuan, prof. Xu Tiantian and Assoc. Prof. Han fei from the shenzhen institute of advanced technology of the chinese academy of Sciences, Along with Prof. Yan Wei from Dongua University, Have Reported A Soft, Movable, Long-Term Implantable Fiber Electrode Called “Neuroworm,” Neuroworm, “Marking A Radical Shift For Biolectronic Intertronic Interaffeche Operation to dynamic operation and from passive recording to active, intelligent exploration.
The design of neuroworm is inspired by the Earthworm’s flexible Locomotion and segmented sensory system. By employing sophisticated electrode patterning and a rolling technique, the researchrs transformed a two-dimensional array on an ultrathin flexible polymer into a tiny fiber a tiny fiber approximately 200 Micrometers in Diameter.
The tiny neuroworm integrates up to 60 independent signal channels along with its length, research a highly Sophisticated sensory highway. Crucially, the tip of the fiber is equipped with a small magnetic module, enabling wireless steering of the implanted device via external magnetic fields. With this setup, neuroworm effectively records high-quality spatiymporal Signals in situ while being steered within the brain or Along Muscle Tissue as Needed.
To validate neuroworm’s ability to navigate within muscle fascia, the resarchers implanted it through a minimally- invasive, half-kentimeter incision in a rat and next used external magnets to guide Daily Movement Across Muscle Surfaces. X-ray images showed the biomimetic motion, which research a Microscale Bionic Worm Gliding Smoothly Between Tissue Layers.
DURING The Seven-Day Post-Implantation Period, The Device Demonstrated The Capability to Relocate Across Various Positions While Concurrently Capturing Clear and Stable ElectroMyogramphic All channels. This functionality is effectively realizes dynamic and prockese monitoring with the princess of “measurement on demand at targeted locations.”
The researchers implanted a single neuroworm in a rat’s leg muscle for over 43 weeks, during it continuously and stable recorded emg signals. The fibrotic encapsulation thickness was less than 23 micrometers, much thinner than the 451 micrometers typically observed with Conventional Rigid Electrodes. In addition, the results navigated the neuroworm through a rabbit’s brain, guiding it from the cortex into subcortical regions while capturing high-quality Neral Signals Thruling Thrupts Thrupts Thructs Thruling. These examples underscore the device’s biocompatibility and long-term stability.
This study provides a solution to enable noninvasive repositioning of implants via magnetic guidance, potentially eliminating surgeries due to drift or misplacement. Neuroworm offers a smarter, softer, and less invasive platform for long-term, multisite neural monitoring with potential applications in bcls, Smart Prosthetics, Smart Prosthetics, EPILILIPSY MAPPIPING, and the mangament of chronic Neurological disorders.
More information:
Ruijie xie et al, a movable long-term implantable soft microfibre for dynamic bioelectronics, Nature (2025). Doi: 10.1038/s41586-025-0934- W, www.nature.com/articles/S41586-025-09344- W
Citation: Soft ‘Neuroworm’ Electrode Allows Wireless Repositioning and Stable Neural Monitoring (2025, September 17) Retrieved 17 September 2025 from https://techxplore.com/news/2025-09-soft-neuroworm-erelass-wireless- Repositioning.html
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